Coyle, MD, professor and acting chair, section of neurology, Stony Brook University INFIRMARY and, director, Stony Brook MS Comprehensive Care Center, Stony Brook, NY. The benefits of TYSABRI are evident in that it can significantly reduce relapse rates, improve cognitive and physical disability and offer freedom from disease activity for many patients, when measured by radiological and clinical measures. Among the expert panel’s recommendations encourages earlier and faster transition from first-collection treatment to TYSABRI. The suggestions also seek to lessen the threshold with physicians for dealing with unacceptable disease activity observed in their patients.Assuming this timing, Cardinal Wellness expects accretion in non-GAAP diluted income per share from continuing functions of greater than $0.15 per share in fiscal 2016, net of the $0.03 to $0.04 per share of interest expense for the related debts financing. Cardinal Health expects accretion in non-GAAP diluted EPS of more than $0.20 in fiscal 2017 and for accretion to be greater thereafter more and more. Furthermore to enhancing the business's generic pharmaceutical distribution business, the acquisition expands Cardinal Health's existing telesales capabilities and programs; broadens the company's portfolio of over-the counter pharmaceutical items; and brings specialized packaging offerings to meet the needs of medical center systems and other organizations.